The paper will argue that a policy of mandatory vaccination against Covid violates human rights. Mandatory vaccination can be pursued for two goals. First, it may be motivated by a desire to reduce the circulation of the virus. The problem with this approach is that the effectiveness of the vaccines in stopping transmission is unclear and in any case seems to wane fairly quickly. In light of this, pursuing this goal by means of a severe interference with the right to physical integrity would be disproportionate. Second, the policy may be aimed at protecting those who get infected with the virus from developing severe illness and thereby also protecting the health services from becoming overburdened. This argument, however, amounts to medical paternalism and violates the principle of patient autonomy. It follows that a policy of mandatory vaccination is unjustifiable and violates human rights.