Since its inception, the international human rights system has served as a stage for significant political contestation. One recent manifestation of this is reflected in the Organization of Islamic Cooperation’s (OIC) creation of an Independent Permanent Human Rights Commission (IPHRC). An examination of the IPHRC’s structure and activities reveals a sophisticated and concerted effort to subvert the foundational premise of human rights for everybody everywhere. This effort advances the relativistic interests of its state masters and emboldens illiberal and authoritarian tendencies on the global stage. Consequently, the paper argues that the failure to mount an effective response to the IPHRC’s emergence as a valid regional rights mechanism risks abdicating human rights diligence in the international arena, and concludes by offering several recommendations aimed at preventing the internal commandeering and discrediting of the international human rights system.